Statins - "kwa" ndi "motsutsana"

Mankhwala olemera a triglycerides ndi cholesterol m'magazi amaonedwa kuti ndi oopsa omwe angapangitse kukula kwa matenda a mtima. Kuchepetsa kuchuluka kwa mankhwalawa kumapatsidwa mankhwala apadera, otengedwa nthawi yaitali. Ndikofunika kuti wodwalayo awerenge zifukwa zonse asanayambe kumwa zakumwa - zotsutsana ndi zotsutsana, samalirani zotsatira za mankhwalawa komanso zovuta za mankhwala.

Mapindu ndi zovulaza za statins kwa thupi

Kupanga kwa kolesterolino kuli magawo angapo apitalo ndi chitukuko cha enzyme yotchedwa mevalonate. Statins imasokoneza mapangidwe ake pachiyambi, motero, kuletsa kupanga triglycerides ndi cholesterol.

Pa kafukufuku wa zachipatala ndi kuyesera, anapeza kuti mankhwala omwe ali mu funso anali ndi zotsatira zotsatirazi:

1. Kuchepetsa kuchuluka kwa cholesterol m'magazi a magazi (okwana - 35-45%, owopsa - ndi 45-60%).
2. Kuchepetsa chiopsezo cha matenda a mtima wa mtima, kupewa matenda a mtima, atherosclerosis, strokes, ischemic.
3. Kuwonongeka kwa kupanga cholesterol mankhwala mu chiwindi.
4. Zonjezerani kuti muli ndi apoliprotein A komanso cholesterol yothandiza.

Komanso, kugwiritsa ntchito statins ndikowongolera thanzi la odwala ngakhale kukhalapo kwa matenda a mtima polimbikitsa ndikuyeretsa makoma a mitsempha. Pa nthawi yomweyi, mankhwalawa alibe mankhwala a mutagenic komanso a carcinogenic.

Ngakhale kuti mankhwalawa akuwoneka bwino, akatswiri posachedwa ali ovomerezeka. Izi ndi chifukwa cha zotsatira zina za kutenga zilembo:

1. Kuchepetsa pa mlingo wa osati kokha kovulaza, komanso cholesterol chokwanira, chomwe chili chofunikira kuti thupi lizikhala bwino, kukhalabe ndi mitsempha ya m'magazi.
2. Kuipa kwa chiwindi parenchyma pofuna kuchepetsa kupanga michere yomwe imayambitsa kolesterolini.
3. Kupeza mwamsanga msangamsanga wa mitsempha yapamwamba ya cholesterol pakutha kwa mankhwala, zomwe zimachititsa kuti mapiritsi azitenga pafupifupi moyo wonse.

Kuwonjezera pa mavutowa, palinso zolephera zambiri zingapo za mankhwala otero.

Zotsatira zoopsa za zilembo

Zowopsa kwambiri ndi izi:

• matenda a asthenic;
• chisokonezo;
• kusowa tulo;
• kudzimbidwa;
• mutu;
• kukondwa;
• kutsekula m'mimba;
• myalgia;
• ululu wamimba;
• migraine;
• chisokonezo;
• paresthesia ndi hypoesthesia;
• chizungulire;
• chiwonongeko cha m'mimba;
• zigawo za amnesia;
• kupweteka;
• cholestatic jaundice;
• kusanza;
• chiwindi;
• anorexia;
• phokoso;
• mpweya mu minofu;
• myositis;
• nyamakazi ya ziwalo zazikulu;
• myopathy;
• ululu pamphepete mwa msana;
• malayalam;
• kupaka khungu;
• anaphylaxis;
• urticaria ndi kuyabwa;
• Matenda a Lyell ;
• shuga;
• chithandizo;
• hypoglycemia;
• kunenepa kwambiri;
• phokoso la edema.

Zina mwa zotsatira zoopsya za zilembo, pali matenda osokonezeka a ubongo. Kafukufuku wambiri wasonyeza kuti nthawi zambiri mankhwala ndi mankhwalawa amaganiziridwa, kukhumudwa kwa chikumbukiro, kugwira ntchito, chidziwitso ndi magalimoto. Odwala ena amavutika ndi zida zochepa za amnesia, pamene munthu sangakwanitse kukumbukira.

Choncho, kutenga zilembo n'kofunikira nthawi zambiri:

1. Matenda a Ischemic ali ndi chiopsezo chowonjezeka cha kudwala kwapakati kapena matenda a mtima.
2. Matenda a matenda ovuta kwambiri.
3. Kuchita opaleshoni yokonzanso pa ziwiya kapena mtima.