Alpha-blockers

Adrainolitics ndi gulu la mankhwala omwe amakhudza adrenergic receptors. Malingana ndi zomwe adrenoreceptors zimakhudzidwa ndi zinthu izi, zimagawidwa mu beta ndi alpha-blockers. Zokonzekera zochokera pazimenezo zimaperekedwa polimbana ndi matenda osiyanasiyana a mtima, mitsempha ya mitsempha, pokhapokha ngati matendawa amatha kusokonekera komanso kuti awonongeke.

Kukonzekera Alpha-blockers

Pali magulu akulu awiri a mankhwala.

Osasankha osankha

Zomwe zimakhumudwitsa zomwe zimachitika pambuyo pake, zomwe zimapangitsa kuti chiwongolero cha zitsulo ndi kuchepa, komanso kutulutsa norepinephrine kwambiri.

Mtsogoleri wamkulu wa gulu loyamba ndi Fentolamine, omwe zotsatira zake ndi kuwonjezera zombo zapansi. Pamene mankhwalawa akuchitidwa intravenously, zotsatira zimapezeka mkati mwa maminiti khumi ndi asanu.

Mu mankhwala, mankhwalawa tsopano akugwiritsidwa ntchito kawirikawiri, koma akhoza kuperekedwa kwa:

• malonda kapena chisanu;
• matenda a pheochromocytoma;
• mavuto owopsa;
• kuwopsya kwa magazi;
• Matenda a Raynaud .

Oimira ena a gulu ili:

• Pyrroxane;
• Tropafen;
• Dihydroergotamine.

Odala Alpha-1-adrenoblockers

Zinthuzo zimakhala ndi ntchito yaikulu komanso nthawi yaitali. Zili ndi zotsatira zabwino pa mlingo wa cholesterol m'magazi, motero amachepetsa chiopsezo cha matenda a atherosclerosis. Kuonjezera apo, zinthuzi sizikusokoneza shuga, musawonjezere chipsinjo ndikusiyana ndi zotsatira zochepa.

Zosankha zamtundu wa alpha ziphatikizapo mndandanda wa mankhwala:

• Doxazosin;
• Ter;
• Prazon.

Ndi mphamvu zawo, mankhwalawa ali patsogolo pa Fentolamine. Chowopsa chawo ndi kuchepetsa kupanikizika pochepetsa kuchepetsa mphamvu. Zida zimayamba kusonyeza pambuyo pa ola limodzi mutatha kudya.

Zisonyezo za ntchito ya Alpha-adrenoblockers

Taganizirani zotsatira za kuchipatala kwa magulu ena a mankhwala:

1. Ndili ndi matenda omwe amabwera m'magazi a Raynaud (matenda a Raynaud), omwe amachiritsidwa ndi zilonda zam'chipatala ndi ma decubitus, ndipo amatha kulamulidwa ndi pheochromocytomas, Fentolamine ndi Tropafen.
2. Maseŵera oyambirira a chitukuko cha prostate adenoma amachiritsidwa ndi Prozazin, zomwe zimapangitsa kuti mkodzo utuluke.
3. Alfa-1-adrenoblockers anali ofala kwambiri pa matenda oopsa. Amakulitsa zombo (kuchokera zing'onozing'ono mpaka zazikuru), potero amachepetsa kupanikizika. Kuchepetsa kupanikizika kumabweretsa kuchepa kwakukulu mu katundu pa kachipatala, komwe kamapangitsa mankhwalawa kukhala ogwira ntchito mu myocardial infarction .
4. Kwa mankhwala a nthawi yaitali, Prazonin ndi Doxazine amagwiritsidwa ntchito.
5. Malo a Fostopolitic amapatsidwa ndi Fentolamin ndi Prazonin.
6. Diabergergotamine imagwiritsidwa ntchito pa migraine, komanso njira zovuta komanso zokondweretsa zozungulira.

Contraindications Alpha-blockers

Musapereke mankhwala kwa anthu omwe ali ndi zolakwika izi:

• bongo;
• chowopsa;
• mtima;
• ndi matenda a impso;
• chidziwitso cha odwala matenda a shuga;
• matenda a ischemic popanda maofesi ofanana a beta-blockers;
• matenda a ubongo.

Kusiyanitsa kwachibale ndi mimba.

Zotsatira zopanda pake zimawonekera monga:

• kupanikizika kwambiri kumatsika;
• kuyambira kwa kutupa;
• mutu;
• kupweteka kwa mtima;
• tachycardia;
• chithunzi;
• kutupa kwa mazira a mucous;
• chisokonezo;
• kusowa tulo;
• ululu minofu.