Otsutsa a calcium amatchedwa gulu lalikulu la mankhwala omwe angalepheretse kutumiza katunduwa kudzera mumasewu apadera kukhala maselo osakanikirana. Akatswiri a zamagetsi amagwiritsa ntchito mankhwalawa mwakhama. Amathandizira kuchiza matenda osiyanasiyana. Chifukwa cha zotsatira zake zenizeni, kupangidwa kwa calcium inayambitsidwa ngati chimodzi mwa zinthu zofunikira kwambiri za pharmacology m'zaka za zana la makumi awiri.
Njira yokhala ndi otsutsa a calcium
Mafuta a calcium ndi ofunika kwambiri kwa thupi. Amachita nawo njira zambiri za moyo. Mitunduyi itangoyamba kulowa m'maselo, njirayi imayambitsidwa, chifukwa choti thupi limagwira ntchito. Ngati ayoni ya calcium imakhala yambiri, maselo amatha kusokoneza kwambiri. Malinga ndi chikhalidwe ichi, kufunikira kwa ziphuphu mu mpweya ndi zakudya zidzakula. Ndipo izi, zowonjezera, zimatsogolera kusintha kuwononga.
Mavitoni a calcium amachepetsanso mchere ndipo samalola kuti tinthu tithe kudutsa mu dera la extracellular mu maselo. Amalimbikitsanso kuteteza magazi komanso kuthamanga kwa magazi.
Kodi akatswiri a calcium amauza liti?
- Ndi vasospastic angina, calcium channel blockers ndi othandiza kwambiri. Monga momwe chiwonetsero chimasonyezera, kugwidwa kumatetezera bwino kuposa njira zina.
- Zotsutsana zimachepetsa msampha, choncho popanda iwo zimakhala zovuta kwambiri kuthana ndi mavuto mu matenda oopsa .
- Kulephera kwa mtima kumakhala kutsutsana. Mankhwala amaletsa njira za calcium kuti azitsatira, koma siziwathandiza aliyense.
- Kukonzekera-mavitamini a calcium otsutsa alibe chowonetseratu kuti akulimbana ndi kubwezeretsanso kachilombo koyambitsa matenda a myocardial. Kulimbana ndi mankhwala osokoneza bongo sikuli bwino kwambiri, koma panthawi yomwe masautsowa ali othandiza kwambiri.
- Odwala osakhazikika angina pectoris amapatsidwa calcium blockers makamaka ndi metoprolol. Kuphatikizana kumeneku kumakhudza kwambiri thupi.
Mndandanda wa mankhwala osokoneza bongo la calcium
Akatswiri amasiyanitsa magulu akulu atatu a mankhwala:
- Zotsatira za phenylalkylamines "zinayamba" ndi Verapamil. Mankhwala a gululi akhoza kuthandizira minofu yonse ya mtima ndi ziwiya. Zili zosayenera kugwirizanitsa ndi beta-blockers, chifukwa pakadali pano kachipatala kamene kamakhala ndi zotsatira ziwiri, chifukwa cha zotsatira za atrioventricular conduction zikhoza kuphwanyidwa.
- Choyamba chochokera kwa dihydropyridine chinali Nifedipine. Cholinga chachikulu cha mankhwala ndizochita vasodilator. Mndandandanda wa otsutsa a calcium a gulu lachiwiri amadziwika ndi kusankha. Choyamba, mankhwala osokoneza bongo amakhudza mitsempha yamakono. Ndipo zilibe zotsatirapo.
- Gulu lachiwirili limaphatikizapo zowonjezera za benzothiazepine, zomwe panopa zikuyimiridwa ndi Diltiazem.
Palinso ena otsutsa mankhwala a calcium. Zotchuka kwambiri ndi zothandiza ndi izi:
- Finoptin;
- Baypress;
- Mzimayi;
- Clentiazem;
- Gallopamil;
- Felodipine;
- Nitrendipine;
- Lacidipine;
- Lercanidipine;
- Isradipine;
- Corinfar;
- Chithunzi;
- Osmo-Adalat;
- Kordafen;
- Amlotop;
- Norvasc;
- Plandil;
- Msewu;
- Dilren;
- Miyala;
- Altiazem.
Otsutsa onse a calcium sakuvomerezedwa kuti aperekedwe mwachangu, ayenera kugwiritsidwa ntchito pokhapokha. Mankhwala amatha kuyambitsa mitsempha yosasinthika, yomwe, monga lamulo, ndi yamphamvu komanso yaitali. Izi zimayambitsa kupatsira mitsempha ya magazi komanso imfa ya ziphuphu.