Chimodzi mwa zizindikiro zofunika, chomwe chimatsimikiziridwa pofufuza magazi, ndi mlingo wa monocytes m'magazi. Monocytes ndi mtundu wa leukocyte. Awa ndi maselo akuluakulu komanso othandiza omwe amawombera mafupa ofiira. Pamodzi ndi kuthamanga kwa magazi, maselo amtundu wa mwana amalowa m'matumbo a thupi ndikuyamba kukhala macrophages. Ntchito yaikulu yazigawozi zamagazi ndi chiwonongeko ndi kuyamwa kwa tizilombo tizilombo toyambitsa matenda omwe alowetsa thupi, ndi kuthetsa mabwinja a maselo akufa. Pogwirizana ndi kuti ma monocytes amachita ntchito yotereyi, amatchedwa "oyang'anira thupi." Ndi ma monocyte omwe amalepheretsa mapangidwe a maselo a thrombi ndi khansa. Kuphatikiza apo, ma monocytes amagwiritsidwa ntchito popanga hematopoiesis.
Chizolowezi cha monocytes m'magazi
Kuti mudziwe ngati zoyenera za magazi zomwe zimapezeka mukufufuza (kuphatikizapo mlingo wa monocytes) zimagwirizana ndi chizoloŵezi, ndikofunikira kuti mukhale ndi lingaliro lachikhalidwe cha monocytes mu zizindikiro zomveka.
Chizoloŵezi cha monocytes m'magazi chimachokera ku 3% mpaka 11% mwa nthenda iliyonse ya leukocyte kapena pafupifupi maselo 400 pa 1 ml ya magazi ammimba (mwachitsanzo, magazi akuzungulira kunja kwa ziwalo zamagazi). Chizoloŵezi cha monocytes m'magazi a akazi chikhoza kukhala chocheperapo malire ndi kuchepetsa 1% ya chiwerengero cha leukocyte.
Komanso mlingo wa maselo oyera umasiyana ndi zaka:
- Mtengo wa monocyte m'magazi a mwana wakhanda umasiyana ndi 3% mpaka 12%;
- ali ndi zaka masabata awiri msinkhu ukhoza kufika 15%;
- mwana wamwamuna wa chaka chimodzi amadziwika kukhala 4-10%.
Pokhala wamkulu, chiwerengero chodziwika cha monocytes m'magazi sichimaposa 8%.
Sinthani mlingo wa monocytes m'magazi
Kuwonjezeka mu monocytes
Kuonjezera mlingo wa monocytes mwana, ngakhale 10%, akatswiri amatha kukhala chete, chifukwa kusintha koteroko kumaphatikizapo njira zakuthupi zakuthupi zomwe zimakhudzana ndi ubwana, mwachitsanzo, zovuta. Kupitiliza kuchuluka kwa monocytes poyerekeza ndi chizoloŵezi choyezetsa magazi mwa munthu wamkulu kumasonyeza kulephera kwa kayendetsedwe ka kayendedwe ka magazi, komanso kukula kwa matenda opatsirana, monga:
- chifuwa chachikulu;
- syphilis;
- kulowa;
- brucellosis ;
- lupus erythematosus;
- nyamakazi ya nyamakazi;
- mycosis, ndi zina zotero.
Kusiyanitsa kwa ma monocyte kumasonyeza kusamba kwa maonekedwe opweteka m'thupi. Kawirikawiri kuwonjezeka kwa maselo oyera kumachitika nthawi yotsatira. Kwa amayi, chifukwa cha kusintha kumeneku ndi kachitidwe kawiri kawiri kwa amayi.
Kuchepetsa ma monocytes
Kutsika kwa mlingo wa monocytes ndi chinthu chosavuta kwambiri kuposa kuwonjezeka kwa chizindikiro ichi. Sizitanthauza kukula kwa matendawa. Mwachitsanzo, amayi ambiri adatsitsa ma monocytes pa nthawi yomwe ali ndi mimba komanso posachedwa. Ndi nthawi ino chifukwa cha kutopa kwa thupi kungasonyeze kuti akudwala magazi m'thupi.
Zowonjezera zina zomwe zimayambitsa kuchepa kwa mavotiki mumagazi:
- Matenda ena opatsirana, poyamba, chiwindi cha typhoid ;
- nthenda yamagazi;
- phwando la corticosteroids ndi cytostatics;
- matenda okhudzana ndi kuwonongeka kwa maselo a ubongo.
Kutsika kwa mlingo wa monocytes nthawi zambiri kumawonedwa panthawi yomwe amagwira ntchito panthawi yopatsira thupi. Koma pakadali pano zimayambitsidwa mwachisawawa ndi mankhwala osokoneza bongo pofuna kuteteza thupi kuti lisakane ziwalo ndi ziwalo zomwe zidapatsidwa.
Mulimonsemo, kusintha kwa magazi omwe amapezeka m'magazi ndi chifukwa choyesa kafukufuku wamankhwala kuti adziwe chifukwa chake, ndipo ngati kuli koyenera, azitsatira njira yoyenera.