Matenda a myeloblastic leukemia

Khansa ya m'magazi, yomwe imachokera m'malo mwa maselo enieni a m'magazi ndi osakanikirana a leukocyte, amatchedwa kuti myeloblastic leukemia. Ngakhale matendawa ndi osowa, matendawa amakula mofulumira ndipo ndi ovuta kuchiza. Kuopsa kwa kuvulala kumawonjezeka ndi ukalamba.

Matenda a myeloblastic - amayambitsa

Konzani momveka bwino zomwe zimapangitsa kuti maselo asinthe mthupi mwake, panthawi yomwe sizingatheke. Zifukwa zomwe zingayambitse kuphwanya izi ndizo:

• kuipitsa chilengedwe;
• kutsekemera kwa dzuwa;
• Kupezeka kwa mankhwala monga benzene ndi formalin;
• Matenda a chibadwa (matenda a Down, Wesler-Fanconi magazi, Bloom's syndrome);
• kupitirira kwakukulu mu mankhwala a mankhwala a cytotoxic.

Chizindikiro cha khansa yoopsa ya myeloblastic leukemia

Malingana ndi kachitidwe ka zamankhwala kavomerezeka kaŵirikaŵiri, matenda omwe akugwiritsidwa ntchito akugawidwa mu subtypes otsatirawa:

• M0 - kuchepetsedwa pang'ono kosalembedwe ka m'magazi;
• Mitsempha yambiri ya myeloblastic M1 popanda chizindikiro cha kusasitsa;
• Mitsempha yambiri ya myeloblastic M2 ndi zizindikilo za kusamba;
• promyelocytic khansa ya m'magazi M3;
• myeloblastic kapena myelomonocytic leukemia ya M4;
• myemiaocytic khansa ya m'magazi ndi kuphatikiza mafupa a eosonophilia M4 (eo);
• mphuno ya monoblast ya khansa ya m'magazi M5a;
• mthempha ya m'magazi yamtundu wa M5b;
• erythrocyte woopsa khansa ya m'magazi M6a;
• khansa yoopsa ya khansa ya m'magazi M6b;
• khansa ya m'magazi ya Mg;
• odwala matenda a khansa ya m'magazi M8.

Mitsempha yambiri ya myeloblastic - zizindikiro

Kumayambiriro kwa kusintha kwa maselo, matendawa sadziwonetseratu. Pambuyo pokhala ndi mafupa ambiri, mafupa a leukocyte amanyamula magazi m'thupi lonse ndipo amatha kukhala m'mimba, nthendayi, chiwindi ndi ziwalo zina.

Gawo loyamba la matendali limakhala ndi zizindikiro:

• kuchepa kwa ntchito zotetezera chitetezo, chifukwa cha zomwe wodwalayo amakhala ndi kachilombo kawirikawiri;
• kufooka;
• kuwonjezeka pang'ono pa kutentha kwa thupi.

Monga malo omwe ali ndi maselo abwino amkati ndi ziwalo zamkati ndi zizindikiro zosinthidwa ndi kusintha, zizindikiro zotsatirazi zimadziwika:

• kupweteka ;
• chibayo;
• magazi ndi m'mimba;
• zovuta zambiri za matenda opatsirana.

Pachigawo chachiwiri, munthu alibe chithandizo chamankhwala chokwanira, nthawi zambiri amamwalira chifukwa cha kuchepa kwa magazi.

Kawirikawiri, magawo apamwamba a chithandizo cha khansa amakhala osakwanira, motero matenda omwe amapezeka kuti ali ndi matenda a khansa ya m'magazi amatha kukhala abwino ndi mankhwala oyenera. Vavy pathogenesis ya matendawa amachititsa kuti izi zidziwikire kumayambiriro kwa mayesero a ma laboratory oyezetsa magazi komanso zizindikiro zomwe zimakhalapo.

Kuchiza kwa khansa yoopsa ya myeloblastic leukemia

Mofanana ndi mitundu ina ya khansa, khansa ya m'magazi imafuna tizilombo toyambitsa matenda omwe ali ndi magawo akulu awiri:

• kuthetseratu maselo omwe adasinthika;
• kuchepetsa chiwerengero cha ma clones mu ziwalo za thupi.

Chithandizo chimayendetsedwa ndi maphunziro angapo ndi kupuma kwafupipafupi komanso nthawi yomweyo kulandira mankhwala omwe amachepetsa kutupa. Kuwonjezera pamenepo, kudya kwa mavitamini, makina osokoneza thupi. Zoipa zotsatira za kulowerera kwa ziwalo ndi maselo owonongeka amaletsedwa ndi mahomoni a glucocorticosteroid. Kuphatikiza apo, amathandizira kuchepetsa ntchito ya ma precursors a leukocyte ndi kukhazikika kwa maselo.

Imodzi mwa njira zothandiza kwambiri zothandizira khansa yamagazi imeneyi ndi kusakaniza mafupa. Njira imeneyi imaphatikizapo kubwezeretsanso minofu yowopsya ndi yathanzi. Mankhwala amasonyeza kuti oposa theka la odwalawo amachiritsidwa kwathunthu.