Kukalamba ndi njira yosapeŵeka yomwe imakhudza munthu aliyense, akuyenda pang'onopang'ono komanso mosalekeza. Komabe, pali matenda omwe ntchitoyi ikukula mofulumira kwambiri, kukhudza ziwalo zonse ndi machitidwe. Matendawa amatchedwa progeria (kuchokera ku Chigriki - asanakwanitse zakale), ndizosawerengeka kwambiri (1 vuto la anthu 4 mpaka 8 miliyoni), m'dziko lathu pali zochitika zingapo zopotoka. Pali mitundu iwiri ikuluikulu ya progeria: Matenda a Hutchinson-Guilford (kupita patsogolo kwa ana) ndi matenda a Werner (omwe akukulirapo akuluakulu). Ponena zakumapeto tidzakambirana m'nkhani yathu.
Werner's Syndrome - chinsinsi cha sayansi
Werner's syndrome inayamba kufotokozedwa ndi chaka cha 1904, dzina lake Otto Werner, yemwe anali dokotala wa ku Germany, koma mpaka pano, chiwerengero cha matendawa sichikudziŵika, makamaka chifukwa cha zochitika zosayembekezereka. Zikudziwika kuti izi ndi matenda a chibadwa omwe amayamba ndi jini mutation, yomwe idalandidwa.
Masiku ano, asayansi agwiritsanso ntchito kuti Werner's syndrome ndi matenda opatsirana kwambiri a autosomal. Izi zikutanthauza kuti odwala omwe amapita patsogolo amapatsidwa nthawi imodzi kuchokera kwa bambo ndi mayi omwe amachititsa kuti akhale ndi chromosome yachisanu ndi chitatu. Komabe, mpaka pano sizingatheke kutsimikizira kapena kukana matendawa pogwiritsa ntchito ma genetic analysis.
Zifukwa za anthu akuluakulu
Chomwe chimayambitsa matenda a ukalamba msanga sichitha. Mazira owonongeka omwe alipo mu ziwalo za jini za makolo a wodwalayo omwe amapita patsogolo sakhudzidwa ndi thupi lawo, koma pokhapokha pokhapokha atayambitsa zotsatira zoopsa, kumudzudzula mwanayo kuti adzidwe mtsogolo ndi kuchoka msanga moyo. Koma chomwe chimapangitsa kuti kusintha kwa mitundu imeneyi kusadziwikiratu.
Zizindikiro ndi matenda a matendawa
Mawonetseredwe oyambirira a Werner's syndrome amapezeka pakati pa zaka 14 ndi 18 (nthawi zina mtsogolo), atatha msinkhu. Mpaka pano, odwala onse amakula bwino, ndipo m'thupi lawo njira zowonongeka kwa zamoyo zonse zimayambira. Monga lamulo, poyamba odwala amavala imvi, yomwe nthawi zambiri imakhala ndi tsitsi. Pali kusintha kansalu khungu: kuyanika, makwinya , hyperpigmentation, khungu lomangiriza, wotumbululuka.
Pali mitundu yosiyanasiyana ya matenda omwe nthawi zambiri imatsagana ndi ukalamba wokalamba: matendawa , matenda a atherosclerosis, matenda a mtima, matenda a m'mimba, mitundu yosiyanasiyana ya mafinya oopsa komanso owopsa.
Matenda a endocrine amawonetsanso kuti: kusakhala ndi zizindikiro zachiwiri zogonana ndi kusamba, kusabereka, mawu apamwamba, kutsekula kwa chithokomiro, matenda a shuga a shuga. Matenda a atrophy ndi minofu, manja ndi miyendo zimakhala zochepa kwambiri, kuyenda kwawo kuli kochepa kwambiri.
Kuwonetsedwa kwa kusintha kwakukulu ndi nkhope za nkhope - zimakhala zowonongeka, khungu kakang'ono kwambiri, mphuno imayamba kufanana ndi mlomo wa mbalame, kamwa imachepa. Ali ndi zaka 30 mpaka 40, munthu yemwe ali ndi munthu wamkulu amakhala ngati munthu wazaka 80. Odwala omwe ali ndi matenda a Werner amakhalabe ndi moyo zaka 50, kufa kawirikawiri ndi khansa, matenda a mtima kapena stroke.
Kuchiza kwa munthu wamkulu wamkulu
Mwatsoka, palibe njira yothetsera matendawa. Chithandizo chimangotanthauza kuchotseratu zizindikiro zowonongeka, komanso kupeŵa matenda omwe amachititsa kuti awonongeke. Chifukwa cha kupaleshoni kwa opaleshoni ya pulasitiki, zinali zotheka kusintha pang'ono mawonetseredwe akunja a kukalamba msanga.
Pakalipano, mayesero amachitika pofuna kuchiza matenda a Werner ndi maselo ofunika. Zilibe chiyembekezo kuti zotsatira zabwino zidzapezeka posachedwa.