MAR-mayeso

Spermogram ndi imodzi mwa mayesero aakulu omwe amatsimikizira kupezeka kwa kusabereka kwa amuna.

Posachedwa, kudalitsidwa kwakukulu kwa immunological amuna osabereka. Pambuyo pa kafukufuku wambiri, zinaonekeratu kuti chifukwa cha izi ndi ma antibodies, omwe amapangidwa ndi amuna m'magazi ndi mapuloteni awo. Koma zotsatira imodzi ya spermogram sikokwanira kuwulula kwathunthu chifukwa cha kusabereka. Choncho, kuti apange chidziwitso cholondola, madokotala amapereka ndondomeko kafukufuku wina wamabambo - MAR-mayeso ("mixed agglutination reaction", omwe amatanthauza "kusokonezeka maganizo").

Antigens pakali pano ndi ziwalo za spermatozoa. Ngati sangathe kulimbana ndi ma antibodies antisperm, ndiye spermatozoon ili ndi membrane yomwe imalepheretsa kuyenda.

Mayeso a MAR amachititsa kuti zitha kuzindikiritsa ma antibodies kapena kutsimikizira kupezeka kwawo.

Kawirikawiri spermogram salola kuvumbulutsira matendawa, chifukwa pakufufuza, spermatozoon, yoonongeka ndi ma antibodies antisperm, imawoneka bwino. Koma pa nthawi yomweyi, sangathe kufesa dzira ndipo kwenikweni ndi lovuta. Mayeso a MAR amachititsa kuti zikhale zotheka kuzindikira chiŵerengero cha spermatozoa choonongeka ndi ma antibodies, ku chiwerengero chonse chomasulidwa mu ejaculate imodzi. Ndipo ndi yekhayo amene amatha kusonyeza nambala yeniyeni ya spermatozoa yathanzi yomwe ingathe kutenga nawo mbali panthawi ya umuna. Ngati zotsatira za mayeso a MAR ndi zoipa, zomwe zikutanthauza kuchuluka kwa ma antibodies, ndiye zimayambitsa zifukwa zina za kusabereka kwa amuna.

Zimayambitsa maonekedwe a anti-antibodies mu thupi lamwamuna

Ndipotu, zifukwa zomwe thupi la munthu limayamba kumenyana ndi maselo ake abwino ndizakuti:

• kulandirira zilonda za m'mimba (kuphatikizapo opaleshoni);
• Kuphwanya msempha pakati pa mitsempha ya magazi ndi ngalande zam'madzi;
• kukhalapo kwa matenda;
• matenda a urogenital;
• pali zifukwa za chiyambi chodziwika;
• Kugonana kwa chiwerewere (kukhalapo kwakukulu kwa mapuloteni akunja akuwonetsedwa ndi thupi ngati pangozi).

Zizindikiro za cholinga cha mayeso a MAR

Chiyeso chokhazikitsa kukhalapo kapena kusapezeka kwa antisperm antibodies chimaperekedwa ngati mwapezeka mu spermogram ya matenda otere a spermatozoa monga:

• chisokonezo;
• gulu;
• kuchepa kuyenda;
• kupezeka kwa nthawi yaitali pakati pa banja;
• Kukonzekera IVF ndi ICSI .

Ngati dokotala wasankha izi, ndi bwino kutenga mayeso a MAR in laboratory yapamwamba yopanga mankhwala, chifukwa zipangizo zamakono zogwiritsidwa ntchito pakugwiritsira ntchito mfundo zofufuzira, zomwe zimakhudza kwambiri kulondola kwa kufufuza kwa mtengo wapatali.

Mayeso a MAR a antitisperm antibodies amasonyeza kuti iwo amadziwika osati pofufuza ubwamuna, komanso pofufuza seramu. Kusintha kwa mayeso a MAR:

1. Kafukufuku wa MAR - pamene zotsatira za kusanthula sizinaulule spermatozoa zowonongeka ndi ma antibodies antisperm.
2. Mayeso olakwika a MAR amatanthauza kuti kuchuluka kwa spermatozoa sikuposa 50%. Chizindikiro ichi chingathenso kuganiziridwa kuti ndichizolowezi.
3. Mayeso a MAR ali abwino, amalingalira pamene kusanthula kunasonyeza kuti kuchuluka kwa spermatozoa mu chipolopolo cha antispermic ndiposa 50%. Chizindikiro ichi chimasonyeza kuti mwayi waumunthu waumunthu umakhala wosabereka.

Ngati mayeso a MAR ali ndi zotsatira zabwino za 100%, ndiye kuti feteleza ya munthu wofunsidwayo ndi yosatheka. Pachifukwa ichi, madokotala amagwiritsa ntchito njira ya IVF ndi ICSI.