Kuwonjezeka kwa bilirubin yonse - kumatanthauzanji?

Kawirikawiri atalandira zotsatira zowonongeka kwa magazi a magazi, wodwala amadziwa kuti wakula mokwanira bilirubin - zomwe zikutanthawuza kuti kuwerengera kwathunthu sikutheka. Chowonadi nchakuti chiwerengero chonse cha pigmentyi ndi chizindikiro cha zizindikiro zachindunji komanso zosawerengeka za bilirubin. Ndi zotsatira izi zomwe zimapangitsa kuti zitheke kuti mupeze dongosolo la zamoyo zomwe zatha kuchitika, ndipo ndi chifukwa chani chosokoneza chiwerengerochi kuchokera pachizolowezi.

N'chifukwa chiyani bilirubin amatha kuyeza magazi?

Zonse zomwe zimakhumudwitsa zambiri za bilirubin zimagawidwa m'magulu anayi. Kusiyanasiyana kumachokera pa magawo a kusinthanitsa kwa chinthucho, komanso 2 kufotokozera:

1. Kuzindikira malo omwe mtundu wa chikasu wonyezimira umawonjezeka (m'chiwindi kapena kunja kwa chiwalo ichi).
2. Mtundu wa kuchuluka kwa bilirubin (mwachindunji kapena mwachindunji).

Malinga ndi njira imeneyi, magulu otsatirawa akuwonjezera kuchuluka kwake kwa mtundu wa chikasu wobiriwira amasiyana:

1. Kuthamanga kwamtundu wa bilirubin - m'maselo a chiwindi, kupanga bile kumasokonezeka, chifukwa cha kutuluka kwake kwadzidzidzika mwachindunji m'matope a chiwindi mkati mwa chiwindi.
2. Kuwonjezeka kwa extrahepatic kwa bilirubin - outflow ya bile imasokonezeka mu dothi la extrahepatic.
3. Kuthamanga kwapadera kwa bilirubin - mu maselo a chiwindi pali kutembenuzidwa kolakwika kwa mtundu wa pigment kukhala mawonekedwe enieni.
4. Kuwonjezeka kwa extrahepatic kwa bilirubin yaulere - kunja kwa chiwindi, zimakhala zobiriwira kwambiri.

Magulu onsewa ali ndi machitidwe owonetsetsa, chifukwa choti n'zotheka kuika kafukufuku woyamba.

Tiyenera kuzindikira kuti ngakhale bilirubin yathunthu ikuwonjezeka pang'ono, kufufuza kwina kumafunika. Sikuti chiwerengero cha nambala ya kuchuluka kwa nkhumba ndi yomasuka ndi kofunikira, komanso chiwerengero chake chiwerengero cha chiwerengero cha mankhwalawa.

Kodi chiwerengero cha bilirubin chowonjezera chimawonjezeka bwanji m'magazi ndi kuchuluka kwa gawo limodzi?

Matenda operekedwa ndi chikhalidwe chofotokozedwa akhoza kukhala intrahepatic ndi extrahepatic.

Gulu loyamba likuphatikizapo:

• chiwindi:
• kachilombo koyambitsa;
• bakiteriya;
• chonchi;
• mankhwala;
• chowopsa;
• choyimira;
• ziphuphu za chiwindi;
• cholestasis ya intrahepatic;
• biliary yoyamba chiwindikiro;
• jaundice ya amayi apakati;
• Matenda a Rotor;
• Matenda a Dabin-Johnson.

Gulu lachiwiri liri ndi matenda otere:

• kupweteka kwapachirombo koopsa;
• kupwetekedwa kwa chiwindi ;
• Aneurysm ya mitsempha yodabwitsa;
• diverticulitis ya duodenum;
• chotupa cha mphuno;
• chokhalitsa, chowopsa ndi chokwanira cholangitis;
• cholelithiasis;
• kutupa kwa duodenum;
• neoplasm mu bile njira.

Kuwonjezeka kwa bilirubin yonse ndi zizindikiro za kuwonjezeka kwa nkhumba yosadziwika - kodi zikutanthauzanji?

Ngati chiwerengero cha ufulu wa bilirubin chikuwonjezeka ndi kuwonjezeka kwa panthawi imodzi pa chiwerengero cha mtundu wa pigment, zifukwa zingathekekanso mkatikati mwa chiwindi cha chiwindi ndi kunja kwake.

Poyamba, pali matenda otere:

• matenda a Kriegler-Nayyar;
• analandira mankhwala osapsa magazi;
• Matenda a Gilbert;
• Matenda a Lucy-Driscola.

Matenda a extrahepatic ndi awa:

• anapeza magazi a hemolytic, kawirikawiri a chiyambi chake chokha;
• kupweteka kwa magazi m'thupi
• sepsis ;
• hemolysis ya erythrocyte m'mimba yatsopano;
• malaria;
• poizoni hemolytic anemia;
• mankhwala a hemolytic anemia.