Triiodothyroxine kapena T3 ndi hormone yotuluka ndi chithokomiro pogwiritsa ntchito tetraiodothyroxine (T4), chifukwa cha kugawanika kwake. Amapangidwa ndi voliyumu yaing'ono, 10 peresenti yokha, komabe ndiyiyi yaikulu yogwiritsira ntchito biologically.
Kawiri kawiri kafukufuku wa ntchito ya chithokomiro ndizofunika kudziwa T3 yaulere - ndi mtundu wotani wa hormone ndipo ndikutani, kudziwa ochepa. Komabe, mtundu uwu wa triiodothyroxine umatengedwa kuti ndi chinthu chofunika kwambiri pa mphamvu yamagetsi m'thupi.
Kodi timadzi timatenda T3 timayankha chiyani?
Chotsatira cha mankhwala omwe akugwiritsidwa ntchito ndi tetraiodothyroxine, yomwe ili ndi ma molecule 4 a iodin. T4 ndi hormone yochepa, yomwe imatulutsa khungu la chithokomiro (pafupifupi 90%).
Pambuyo pa kupatukana kwa molecule imodzi ya ayodini kuchokera ku tetraiodothyroxine, T3 imapangidwa. Hormone imeneyi imagwira ntchito mobwerezabwereza kuposa T4, imayambitsa njira yogawira mphamvu, kuyambitsa ntchito zamanjenje, kuphatikizapo ntchito ya ubongo. Ndipotu, triiodothyroxine ndizomwe zimapangitsa kuti thupi lonse liziyenda bwino.
Nthawi ina T3 imalowa m'magazi, imamanga mapuloteni. Amagwira ntchito yoyendetsa katundu, kupereka ma hormone kwa ziwalo ndi ziphuphu, kumene kuli kusowa kwachangu. Mzere wa triiodothyroxine muzofukufuku umatchedwa wobadwa.
Kachigawo kakang'ono ka mahomoni kamakhalabe m'magazi osatetezedwa, ndiye T3 ndi ufulu. Maganizo ake amadziwika kuti ndi omwe amachititsa kuti aphunzire za chithokomiro, chifukwa triiodothyroxine imakhala yosagwira ntchito ndipo imatulutsa zotsatirazi.
Thimoni yamatenda ya T3
Ma laboratori osiyana amagwiritsa ntchito malire awo enieni pa chinthu chomwe chilipo. Zimadalira njira yowerengera ndondomeko yake, magawo a muyeso ndi mphamvu ya zipangizo zomwe amagwiritsa ntchito.
Pofuna kudziwa molondola za immunochemiluminescent analyzers, zomwe zidafotokozedwa zili ndi 2.62 mpaka 5.69 nmol / l. Pamaso pa zipangizo zochepa zochepa, pamtunda wa chizoloŵezichi nthawi zambiri amawonetseredwa pamwamba, 5.77 nmol / l.
Chifukwa cha ma hormone T3 ndi ufulu?
Kusiyanitsa kwa chizoloŵezi choyenera nthawi zambiri kumakhala kuwonetsa zochitika zosiyanasiyana za thupi zomwe zimayambitsidwa ndi mankhwala enaake.
Zifukwa zazikulu zowonjezera ma hormone T3 kwaulere:
- kulemera kwakukulu kwa thupi;
- maphunziro omaliza a hemodialysis;
- kupweteka kwa chithokomiro (kanthaŵi) pambuyo pobereka;
- myeloma kuphatikizapo matenda akuluakulu a immunoglobulin G;
- subacute kapena acute thyroiditis;
- matenda aakulu a chiwindi;
- matenda a nephrotic pokonza glomerulonephritis;
- HIV;
- choriocarcinoma;
- chonchi;
- porphyria ;
- chowopsa;
- kulandirira mahomoni a chithokomiro, mitundu yosiyanasiyana ya kulera, methadone, cordarone.
Ndikofunikira kwambiri kuti tithe kuyang'ana kwa odwala matenda a endocrinologist ngati ma hormone a T3 omasuka ataukitsidwa - mankhwala amayamba nthawi, amathandiza kupeŵa zovuta za matenda omwe amadziwika, kuti asamachepetse kukula kwa mankhwala osokoneza bongo ndi metastasis.
Nchifukwa chiyani hormone T3 imasulidwa?
Kutsika kwa kuchuluka kwa tri-thirotoxin osagwidwa si koopsa monga kuwonjezeka kwake. Zifukwa zazikulu za zotsatira zoterezi
- kusakwanira kwa ntchito ya adrenal;
- matenda;
- zakudya zochepa mu mapuloteni;
- chithandizo ;
- kuchira ku matenda aakulu;
- mankhwala ndi statins, anabolic, anti-inflammatory drugs, antithyroid mankhwala, steroids;
- kulandiridwa kwaposachedwapa kwa njira zowonjezera.