Ampicillin ndi mankhwala osokoneza bongo omwe amachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo ta penicillin angapo. Chochita cha mankhwala ogwiritsira ntchito mankhwalawa chikuwongolera kuwonongedwa kwa nembanemba ya maselo a tizilombo tating'onoting'ono, komanso kuponderezedwa kwa njira zamagetsi, ndiko kuti, kaphatikizidwe pakati pa zipolopolo za maselo a bakiteriya, zomwe zimawalepheretsa kuchulukitsa ndi kuwononga maselo okha. Zotsatira za Ampicillin ndizovuta kwa mabakiteriya, Gram-negative bacteria, komanso matenda opatsirana m'mimba.
Mankhwalawa ndi acid. Pachilumbachi salola kuti madzi a m'mimba azikhudza kwambiri mankhwalawa pamene atayamwa, kuyamwa ndi 40% yokha. Kukwanira sikuchitika, mankhwalawa amachotsedwa popanda biotransformation. Ampicillin ndi othandiza pamene ma antibayotiki ena sangathe kupirira matendawa.
Zizindikiro zogwiritsa ntchito Ampicillin
Popeza Ampicillin ali ndi zochitika zambiri, kuwononga mitundu yambiri ya mabakiteriya, amagwiritsidwa ntchito pochizira matenda osiyanasiyana mu machitidwe osiyanasiyana a thupi.
1. Matenda opatsirana pogonana ndi ENT ziwalo za Ampicillin zimapatsidwa chithandizo cha matenda oterowo:
- pharyngitis;
- tonsillitis;
- sinusitis;
- angina;
- chofiira;
- kupweteka;
- chitsulo;
- kupuma kwa mapapo;
- chibayo;
- bronchopneumonia;
- pleurisy;
- otitis media.
2. Ndi matenda a maginito ndi matenda a impso, maantibayotiki amathandizira matenda awa omwe amachititsidwa ndi enterococcus, proteus, E. coli kapena matenda osakaniza:
- chithunzi;
- pyelonephritis;
- urethritis;
- cystitis;
- gonorrhea;
- cervicitis.
3. Matenda a dongosolo la bi-biliary Ampicillin amasonyezedwa kuti:
- cholecystitis;
- cholangitis.
4. Ampicillin imaperekedwa kwa amayi apakati pamene matenda a chlamydial amapezeka, ngati pali kusagwirizana kwa Erythromycin.
5. Matenda opatsirana amtundu wofewa ndi khungu, monga:
- impetigo;
- nkhope;
- dermatosis gawo lachiwiri la matenda;
- mabala a purulent.
6. Mu matenda opatsirana pogwiritsa ntchito matendawa:
- rumatism;
- nyamakazi;
- osteomyelitis ;
- chithandizo;
- pasteurellosis.
7. Pamene timapepala ta m'mimba timakhudzidwa ndi matenda monga:
- salmonellosis;
- salmonella;
- kamwazi;
- chiwopsezo cha typhoid;
- paratyphus;
- peritonitis.
Komanso, Ampicillin imaperekedwa ku matenda oopsa komanso owopsa monga meningitis, endocarditis, sepsis (septicemia kapena matenda a magazi), matenda a odontogenic a m'kamwa.
Ampicillin mu chithandizo cha strep throat
Angina ndi matenda opweteka kwambiri owopsa chifukwa cha gulu la streptococcal la mabakiteriya. Njira yothandiza kwambiri ya mankhwala a streptococcal angina ndi mankhwala ndi maantibayotiki a mchere wa penicillin, makamaka Ampicillin masiku 10-14.
Pankhani imeneyi, chitukuko cha matendawa chimalepheretsedwa, chifukwa kugawidwa ndi kukula kwa mabakiteriya kumatsekedwa, kenako matendawa amatha chifukwa cha kuwonongeka kwamuyaya kwa makoma, kusakhoza kubwezeretsa ndi imfa yomaliza ya mabakiteriya. Kafukufuku amasonyeza kuti mpumulo umabwera tsiku lachiwiri la kumwa mankhwala, ndipo patatha masiku 4-5 zizindikiro zimachoka. Pa chithandizo cha streptococcal angina, mlingo wa Ampicillin akuluakulu umakhala pakati pa 0.25 ndi 0,5 magalamu. Tengani mankhwala 4 pa tsiku.
Kuchiza kwa chibayo ndi ampicillin
Chibayo chimadziwika kuti ndi matenda opatsirana omwe amabwera ndi mabakiteriya. Ndikofunika kuchiza chibayo mwachidziwitso, koma njira zazikulu za "kupambana" pa matenda ndi mankhwala opha tizilombo. Ampicillin amakumana ndi ntchito imeneyi bwino, chifukwa chake nthawi zambiri madokotala amatipatsa. Ngakhalenso bwino, ngati mumagwiritsa ntchito Ampicillin-sulbactam, popeza ili ndi ntchito yowonjezereka ndipo imathetsa mabakiteriya omwe sagwirizana ndi Ampicillin wamba. Monga lamulo, ndi chibayo, mankhwala ophera ma antibayotiki amauzidwa mwamphamvu kuti apite mwamsanga mwazi.