Hormone yochititsa chidwi (FSH) ndi hormone yomwe imapangidwa ndi hypothalamic-pituitary system, makamaka - muzinthu zamakono. Kukonzekera kwa kupanga kwake kumapangidwa ndi hypothalamus, ndipo ma FSH ambiri amadalira molingana ndi kuchuluka kwa mahomoni ogonana m'magazi.
Pang'ono ndi pang'ono kuchepa kwao, kukakamizidwa kwa FSH kupanga kumachitika, ndipo pamwambamwamba - kaphatikizidwe ka hormone-yotulutsa timadzi timachepetsa. Komanso amachepetsanso kaphatikizidwe ka FSH inhibin-B, yomwe ili m'maselo a mazira ndi m'magazi amtundu wa amuna.
Mbali za kupanga mahomoni
Kuphatikizidwa kwa FSH sizowonjezereka, koma khalidwe lokhalitsa. Choncho, pamene mankhwala opangidwa ndi follicle omwe amachititsa kuti thupi liwonongeke, limakhala lokhalokha m'magazi azimayi, chiwerengero chake chimakula kwambiri ndipo chimakhala choposa 2, komanso nthawi ziwiri. Kenaka mlingowo umachepa pang'onopang'ono. Nkhanza zapamwamba zimapezeka mu follicular stage ya kusamba.
Maselo a FSH mu nthawi zosiyana za moyo wa mkazi
Zomwe zimachitika m'magazi a mayi wina alibe magazi ndipo nthawi zambiri zimakhala zogwirizana ndi 1.7-135 IU / l.
Choncho zomwe zili m'kati mwa magazizi zimadalira gawo lapadera la kusamba. Mu follicular gawo , FSH nthawi zambiri 3.49-13 IU / L, mu luteal amachepetsa - 1.69-7.7. Mahomoni ambiri amafika pa nthawi ya ovulation - 4.69-22 IU / l. Pa nthawi yomwe mayi ali ndi mimba, ma FSH amachepetsa kwambiri, ndipo amatha kulemera kwa 0.01-0.3 IU / L.
Pa nthawi ya postmenopausal, zomwe zili ndi FSH zikuwonjezeka, zomwe zimayambitsa kusokoneza kapangidwe ka estradiol ndi progesterone. Panthawiyi, FSH yayamba kufika 26-135 IU / l.
Zomwe zimayambitsa mahomoni zimakhala pansi pa chizoloŵezi, zomwe zimayambitsa chitukuko cha:
- matenda a Callman;
- kusowa kwa ma hormone ndi chikoka cha pituitary;
- zotupa za m'mimba mwake, mitsempha.
Komanso, kuwonjezereka kwa mahomoni osakanikirana omwe ali pamwambapa, kungayambitse matenda monga:
- matenda a gonads;
- chotupa chamatope;
- ovarian cyst;
- kugonjetsedwa kwa gonads;
- kutha msinkhu msinkhu.
Meaning
FSH, yokonzedwa mu thupi lachikazi, imalimbikitsa kusasitsa kwa follicles ndikuonetsetsa kuti akukonzekera njira ya ovulation. Timadzi timene timayendetsa gawo loyambirira la kusamba kwake, kupyolera m'madzi. Pansi pa mphamvu yake, follicle imakula kwambiri ndikuyamba kupanga estradiol . Kumapeto kwa follicular gawo, kuchuluka kwa FSH kwawonjezeka. Kenaka follicle bursts, ndipo kuchokera pamenepo dzira lokhwima limachoka pamtunda wa piritoneal, ndiko kuti, kuyendayenda kumachitika.
Pakati pa gawo lachiwiri la zozungulira, luteal, FSH imalimbikitsa pulojekiti yeniyeni ya progesterone. Mkazi akamakula ali ndi zaka 45 mpaka 50, amayamba kusamba, kumene estradiol ndi progesterone sizipangidwanso ndi mazira, zomwe zimabweretsa kuwonjezeka kwa thupi la FSH.
FSH imapezeka mwa amuna, koma pamaganizo ochepa kwambiri. Hormone iyi imayambitsa njira ya spermatogenesis mwa anyamata. Ndi FSH yomwe imathandizira kuti chitukukochi chikhale chonchi komanso chiwonjezere testosterone.
Makanda ambiri amawoneka ngati ana atabadwa. Kwa anyamata amachepetsa kwa theka la chaka, ndipo atsikana - amafika pafupipafupi kapena amawerengera zaka 1-1,5. Nthawi yotsatira zomwe zokhutira zikuwonjezeka pokhapokha zikafika m'badwo wa kusintha, pamene FSH imayendetsa njira yakutha msinkhu.